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Effective treatment of vancomycin nephrotoxicity with continuous venous-venous haemodiafiltration (CVVHDF) in a paediatric patient.
Journal of Clinical Pharmacy and Therapeutics ( IF 2 ) Pub Date : 2020-05-18 , DOI: 10.1111/jcpt.13181
Meng Lv 1 , Shuli Ma 1 , Nan Chen 1 , Yan Liu 2 , Zutao Yu 3
Affiliation  

Vancomycin removal by dialysis uses methods that differ in type of dialysis membrane, dialysis fluxes and duration, ultrafiltration rate and Kt/Vurea (K = dialyser urea clearance, t = time on dialysis and V = total body water) in case of nephrotoxicity. We applied continuous venous‐venous haemodiafiltration (CVVHDF) to treat a paediatric case of vancomycin nephrotoxicity caused by high serum trough concentrations.

中文翻译:

小儿患者持续静脉-静脉血液透析滤过(CVVHDF)有效治疗万古霉素肾毒性。

透析去除万古霉素时使用的方法在肾毒性情况下会有所不同,这些方法的透析膜类型,透析通量和持续时间,超滤速率和Kt / V尿素(K =透析液尿素清除率,t =透析时间,V =全身水)不同。我们应用连续静脉血液透析滤过(CVVHDF)治疗小儿高血药浓度引起的万古霉素肾毒性。
更新日期:2020-07-06
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