Among the hundreds of recombination events initiated at meiosis, only a subset is selected to become crossovers. In this issue of Developmental Cell, Sandhu et al. (2020) reveal that budding yeast Mph1/FANCM dismantles recombination events between sister chromatids at early meiosis, thus favoring recombination with homologs.

中文翻译：

---

不要忘记姐姐：指导减数分裂的双链断裂修复。

在减数分裂引发的数百个重组事件中，仅选择一个子集进行交换。在本期《发育细胞》中，Sandhu等人。（2020）揭示出萌芽的酵母Mph1 / FANCM消除了减数分裂早期姐妹染色单体之间的重组事件，从而有利于同系物的重组。