Patients presenting with pancreatic ductal adenocarcinoma in an advanced inoperable stage receive chemoradiotherapy. Endoscopic ultrasound guided radiofrequency ablation (EUS-RFA) has been proposed as a new therapeutic option for these patients alongside chemotherapy. The evaluation of treatment response is mainly based on radiological evaluation of the changes in tumour size. Unfortunately, the currently available radiological methods cannot clearly differentiate between necrotic tissue and viable tumour. EUS elastography is an ultrasound technique that can grade the hardness of a lesion and classify it as benign, inflammatory or neoplastic as previously reported. This case report of 2 patients shows that using EUS elastography is beneficial in characterizing the nature of the changes occurring to the tumour mass following EUS-RFA of pancreatic tumour.

晚期无法手术的胰腺导管腺癌患者接受放化疗。内窥镜超声引导射频消融（EUS-RFA）已被建议与化疗一起作为这些患者的新治疗选择。治疗反应的评估主要基于肿瘤大小变化的放射学评估。不幸的是，当前可用的放射学方法不能清楚地区分坏死组织和活瘤。EUS弹性成像是一种超声技术，可以对病变的硬度进行分级，并将其分类为良性，炎性或赘生性，如先前报道。