This work was mainly aimed to synthesize new ceramic composites based on nano-bioactive glass (nBG) and magnesium phosphate ceramic (MgP) with different ratios using the sol-gel approach in order to overcome the limitations of both materials. The glass was based on 85SiO₂-10CaO-5P₂O₅ (mole %), and MgP was based on the formula; Mg₃(PO₄)₂. The obtained composites were characterized by DTA, XRD, FTIR, SEM/EDX and Zeta potential techniques. The in vitro bioactivity test was carried out in SBF, and the cell viability test was conducted by culturing the composites with human normal fibroblast cell line (BJ1). The results of XRD analyses showed that there were often no strong diffraction peaks detected which indicated the amorphous nature of the ceramic composites. Moreover, soaking of the ceramic composites in SBF exhibited that addition of MgP to nBG was increased the degradation of the latter one, and nBG was improved the formation of apatite crystals on MgP ceramic. Moreover, the cell viability results showed that MgP was showed significant higher viability than nBG at high concentrations, and it improved the viability of nBG in the ceramic composites.

这项工作的主要目的是使用溶胶-凝胶法合成基于不同比例的纳米生物活性玻璃（nBG）和磷酸镁陶瓷（MgP）的新型陶瓷复合材料，以克服两种材料的局限性。玻璃基于85SiO ₂ -10CaO-5P ₂ O ₅（摩尔％），并且MgP基于式；镁₃（PO ₄）₂。通过DTA，XRD，FTIR，SEM / EDX和Zeta电位技术对所得复合材料进行表征。在SBF中进行体外生物活性测试，并通过与人正常成纤维细胞系（BJ1）培养复合物进行细胞活力测试。XRD分析的结果表明，通常没有检测到强的衍射峰，这表明了陶瓷复合材料的无定形性质。此外，将陶瓷复合材料浸泡在SBF中显示出，向nBG中添加MgP可以增加后者的降解，而nBG可以改善MgP陶瓷上磷灰石晶体的形成。此外，细胞生存力结果表明，在高浓度下，MgP的生存能力明显高于nBG，并且提高了陶瓷复合材料中nBG的生存能力。