Herein, a series of conjugates combining bile acid and terpyridine units were developed. Based on the unique rigid skeleton and excellent amphiphilicity of bile acid fragment, the aggregation properties of three conjugates are finely regulated and the resulted aggregates can strongly confine and tune the rotation of terpyridine units to endow the three conjugates with excellent different AIE properties. Furthermore, with the excellent metal coordination properties, terpyridine units endow the conjugates with excellent metal response properties and lead to various colourful complexes. The supramolecular assembly morphology can also be well controlled by the metal ions. These biological conjugates with controllable AIE properties and metal tunable fluorescence and supramolecular assembly properties may provide a new avenue for the bioimaging and drug controllable delivery system.

本文中，开发了一系列结合胆汁酸和叔吡啶单元的缀合物。基于胆汁酸片段独特的刚性骨架和出色的两亲性，可以对三种结合物的聚集特性进行精细调节，并且所产生的聚集体可以强烈地限制和调节三联吡啶单元的旋转，从而赋予这三种结合物以优异的AIE特性。此外，由于具有出色的金属配位性能，三联吡啶单元使缀合物具有出色的金属响应性能，并导致各种有色配合物。金属分子也可以很好地控制超分子组装形态。