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Fetal gender, serum human chorionic gonadotropin, and testosterone in women with preeclampsia
Hypertension in Pregnancy ( IF 1.5 ) Pub Date : 2020-05-14 , DOI: 10.1080/10641955.2020.1765174
Zakia M Ibrahim 1 , Eman A Kishk 1 , Mahmoud S Elzamlout 1 , Amal M Elshahat 1 , Omima T Taha 1
Affiliation  

ABSTRACT Objectives Evaluation of the association between fetal gender, serum beta-human chorionic gonadotropin, and serum testosterone, and preeclampsia. Methods Case-control study conducted at the Obstetrics and Gynecology Department. 120 patients divided into study group (patients with preeclampsia subdivided into mild and severe) and control group (normotensive women). Interventions Fetal gender was determined. Serum testosterone and HCG levels were estimated at 32 weeks or at the time of diagnosis of preeclampsia (study group) or recruitment (control group). Results Positive association between the male gender of the fetus and preeclampsia. Increased HCG and Testosterone were associated with developing preeclampsia. Conclusion The mechanism of preeclampsia could be androgen-mediated. There is a significant correlation between serum HCG and testosterone and preeclampsia.

中文翻译:

先兆子痫女性的胎儿性别、血清人绒毛膜促性腺激素和睾酮

摘要 目的 评估胎儿性别、血清β-人绒毛膜促性腺激素和血清睾酮与先兆子痫之间的关联。方法病例对照研究在妇产科进行。120例患者分为研究组(先兆子痫患者分为轻度和重度)和对照组(血压正常的女性)。干预措施 确定胎儿性别。在 32 周或诊断先兆子痫(研究组)或招募(对照组)时估计血清睾酮和 HCG 水平。结果 胎儿男性与先兆子痫之间呈正相关。HCG 和睾酮增加与先兆子痫的发生有关。结论先兆子痫的发病机制可能是雄激素介导的。
更新日期:2020-05-14
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