Two new labdane diterpenoids denoted Scoparicol A (1) and Scoparicol B (2) were isolated from the aerial parts of Scoparia dulcis L. The new structures were determined by various spectroscopic techniques, including ¹H NMR, ¹³C NMR, HMBC, HSQC, ¹H-¹HCOSY, ROESY, and HRESIMS. Both compounds were tested for their attenuating effect on palmitate-induced viability at 25 and 50 μM, separately. The results showed that the two new compounds significantly attenuated palmitate-induced viability in MIN6 cells.

中文翻译：

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两种新的拉丹烷中的拉丹烷二萜类化合物可减弱棕榈酸酯诱导的MIN6细胞活力

从Scoparia dulcis L的地上部分中分离出两种新的拉丹烷二萜化合物Scoparicol A（1）和Scoparicol B（2）。通过多种光谱技术确定了新结构，包括¹ H NMR，¹³ C NMR，HMBC，HSQC，¹ H- ¹ HCOSY，ROESY和HRESIMS。分别测试了这两种化合物在25和50μM下对棕榈酸酯诱导的活力的衰减作用。结果表明，这两种新化合物显着减弱了MIN6细胞中棕榈酸酯诱导的活力。