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Human closed and open apex premolar teeth express different toll-like receptor.
Molecular Genetics & Genomic Medicine ( IF 2 ) Pub Date : 2020-05-13 , DOI: 10.1002/mgg3.1268 Reza Jafari 1 , Razieh Karamzadeh 2, 3 , Faezeh Pesaran Hajabbas 4 , Fereshteh Sayyadizadeh 5 , Zahra Chekini 2 , Samaneh Aghajanpour 2, 6 , Leila Shakeri 4 , Kiumars Nazarimoghaddam 4 , Reza Aflatoonian 2
Molecular Genetics & Genomic Medicine ( IF 2 ) Pub Date : 2020-05-13 , DOI: 10.1002/mgg3.1268 Reza Jafari 1 , Razieh Karamzadeh 2, 3 , Faezeh Pesaran Hajabbas 4 , Fereshteh Sayyadizadeh 5 , Zahra Chekini 2 , Samaneh Aghajanpour 2, 6 , Leila Shakeri 4 , Kiumars Nazarimoghaddam 4 , Reza Aflatoonian 2
Affiliation
The innate immune activation which promotes inflammation responses in the dental pulp tissue leads to the progression of dentin caries. Accordingly, toll‐like receptors (TLRs) are key molecules of the innate immune system that identify pathogen‐associated molecular patterns (PAMPs) on microorganisms and may have a critical role in a dental injury. Therefore, this study aimed to investigate the expression of TLR2 , TLR3 , and TLR4 in the human dental pulp of opened and closed apex teeth.
中文翻译:
人的封闭和开放式尖牙前磨牙表达不同的收费样受体。
促进牙髓组织中炎症反应的先天免疫活化导致牙本质龋病的发展。因此,toll样受体(TLR)是先天免疫系统的关键分子,可识别微生物上的病原体相关分子模式(PAMPs),并可能在牙齿损伤中起关键作用。因此,本研究旨在研究TLR2,TLR3和TLR4在先端和闭合尖牙的人牙髓中的表达。
更新日期:2020-07-06
中文翻译:
人的封闭和开放式尖牙前磨牙表达不同的收费样受体。
促进牙髓组织中炎症反应的先天免疫活化导致牙本质龋病的发展。因此,toll样受体(TLR)是先天免疫系统的关键分子,可识别微生物上的病原体相关分子模式(PAMPs),并可能在牙齿损伤中起关键作用。因此,本研究旨在研究TLR2,TLR3和TLR4在先端和闭合尖牙的人牙髓中的表达。