As the global sulphur limit implemented by the International Maritime Organization (IMO) and the further development of sulphur emission reduction technologies, the effects of Emission Control Areas (ECAs) on reducing the sulphur emissions from ships will be reduced gradually. To explore the necessity of ECAs in the near future, this paper introduces the fictitious sulphur emission permit allocated to shipping carriers for our considered region. We propose an ECA location problem, which determines the location of ECAs in order to minimize the impact of sulphur emissions on human health, while satisfying the constraint on the fictitious sulphur emission permit. A mixed-integer linear programming model is proposed for our investigated problem. Numerical experiments are carried out by using our proposed model applied to China and Africa, where the sulphur emissions at different sites are estimated via the fuel consumption calculated by collecting data from liner carriers. Results show that, for the case of China, the Bohai Rim, the Yangtze River Delta and the Pearl River Delta have a high probability for establishing ECAs. For the case of Africa, the Guinea Bay and South Africa have a high probability for establishing ECAs.