Disulfiram has been used successfully over the last 6 decades in the long-term management of alcohol dependence. The patient taking disulfiram is deterred from consuming alcohol due to the knowledge that its reaction with ethanol (DER) (Brewer and Streel, 2018; De Sousa, 2019). The DER consists of uneasiness, nausea, flushing, chest and abdominal discomfort and can be serious in some cases. Patients who have experienced this reaction rarely would wish to experience the same again (Savas and Güllü, 1997). Patients on disulfiram therapy are known to develop DERs when exposed to either food cooked in alcohol, certain sauces that may have alcohol content and due to excessive use of after shaves or scents that may have alcohol content (Savas and Güllü, 1997). The start of the COVID-19 pandemic saw a sharp rise in the use of hand sanitizers as a means of protection from the virus (WHO, 2009). Most sanitizers have ethanol as their base.

中文翻译：

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因手部消毒而戒酒的患者中的双硫仑乙醇反应。

在过去 6 年中，双硫仑已成功用于酒精依赖的长期管理。服用双硫仑的患者由于知道其与乙醇 (DER) 发生反应而被阻止饮酒（Brewer 和 Streel，2018 年；De Sousa，2019 年）。DER 包括不安、恶心、潮红、胸部和腹部不适，在某些情况下可能很严重。经历过这种反应的患者很少希望再次经历同样的事情（Savas 和 Güllü，1997）。已知接受双硫仑治疗的患者在接触酒精烹制的食物、某些可能含有酒精的酱汁以及过度使用可能含有酒精的须后水或香味时会发生 DERs（Savas 和 Güllü，1997 年）。在 COVID-19 大流行开始时，使用洗手液作为预防病毒的手段急剧增加（世卫组织，2009 年）。大多数消毒剂都以乙醇为基础。