Abstract

In this review the advantages of the gonadotropin-releasing hormone agonist (GnRHa) trigger are discussed beyond those immediately associated with ovarian hyperstimulation syndrome (OHSS) prevention. The GnRHa trigger concept has sparked the development of novel protocols, enriching the assisted reproductive technology (ART) armamentarium for the benefit of present and future patients. Thus, GnRHa trigger already has a pivotal role, not only for the standard in vitro fertilisation (IVF) patient, but also for patient groups like oocyte donors, cancer patients, patients with poor ovarian reserve, and patients with immature oocyte syndrome and empty follicle syndrome. Herein, we discuss the importance of the GnRHa-elicited midcycle FSH surge and the potential improvement in oocyte yield and embryo competence.

摘要

在这篇综述中，讨论了促性腺激素释放激素激动剂（GnRHa）触发的优点，而不仅仅是与卵巢过度刺激综合症（OHSS）预防相关的优点。GnRHa触发概念激发了新型方案的开发，丰富了辅助生殖技术（ART）武器库，使现在和将来的患者受益。因此，GnRHa触发不仅已经对标准体外受精（IVF）患者，而且对于诸如卵母细胞供体，癌症患者，卵巢储备不良的患者以及卵母细胞不成熟综合征和卵泡未成熟的患者组都具有举足轻重的作用综合症。在这里，我们讨论GnRHa引起的中期周期FSH激增的重要性，以及卵母细胞产量和胚胎能力的潜在改善。