ABSTRACT The spontaneous preparation of well-defined functional nanoscale systems is very important, since this formulation process requires additional resources, external supply of energy and time. One of the widely used methods of their spontaneous formation is the self-assembling process using of various calixarene building blocks. The relative simplicity of the synthesis of initial calixarene skeleton, the possibility of modifying both of its rims with a wide range of chemical groups, and the presence of a hydrophobic aromatic cavity allow the use of calixarenes to create both individual and mixed aggregates. This article summarises different types of self-assembled calixarene-based amphiphilic aggregates with useful properties. Potential applications of these aggregates in biological nanotechnology are also described. Graphical abstract

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用于生物医学应用的基于杯芳烃的纯和混合组件

摘要 定义明确的功能性纳米尺度系统的自发制备非常重要，因为该配方过程需要额外的资源、外部能量和时间供应。它们自发形成的广泛使用的方法之一是使用各种杯芳烃结构单元的自组装过程。初始杯芳烃骨架合成的相对简单性、用广泛的化学基团修饰其两个边缘的可能性以及疏水性芳香腔的存在允许使用杯芳烃来产生单独的和混合的聚集体。本文总结了具有有用特性的不同类型的自组装杯芳烃基两亲聚集体。还描述了这些聚集体在生物纳米技术中的潜在应用。图形概要