We investigated the clinical effectiveness of Eye-Search, a web-based therapy app designed to improve visual search times, in a large group of patients with either hemianopia, neglect or both hemianopia and neglect. A prospective, interventional cohort design was used. For the main, impairment-based outcome measure (average visual search time), the within-subject control was affected vs. unaffected side. Four hundred and twenty-six participants who fitted the inclusion criteria completed all 4 time points (1200 therapy trials). We found a significant three-way interaction between therapy, side and group. Eye-Search therapy improved search times to the affected visual field of patients with either hemianopia alone or neglect and hemianopia, but not those with neglect alone. Effect sizes were moderate to large and consistent with previous studies. We found a similar significant interaction between therapy and group for the patient-reported outcome measure "finding things" that most closely matched the impairment-based outcome (visual search). Eye-Search therapy improves both impairment-based and patient-reported outcome measures related to visual search in patients with hemianopia alone or hemianopia and neglect.

中文翻译：

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Eye-Search疗法对偏盲、忽视或偏盲、忽视患者的临床疗效

我们调查了 Eye-Search 的临床有效性，Eye-Search 是一种基于网络的治疗应用程序，旨在提高视觉搜索时间，在大量偏盲、忽视或偏盲和忽视的患者中进行。使用了前瞻性、介入性队列设计。对于主要的、基于损伤的结果测量（平均视觉搜索时间），受试者内控制受到影响与未受影响的一侧。符合纳入标准的 426 名参与者完成了所有 4 个时间点（1200 项治疗试验）。我们发现治疗、侧方和团体之间存在显着的三向相互作用。Eye-Search 疗法改善了对单独偏盲或被忽视和偏盲患者的受影响视野的搜索时间，但不能改善单独被忽视的患者的视野。效果大小从中等到大，与以前的研究一致。对于患者报告的结果测量“发现事物”，我们发现治疗和组之间存在类似的显着交互作用，与基于损伤的结果（视觉搜索）最匹配。Eye-Search 治疗改善了与单独偏盲或偏盲和忽视患者的视觉搜索相关的基于损伤和患者报告的结果测量。