Effectiveness of a 12-week cognitive training (CT) programme for community-dwelling patients with dementia was evaluated on various cognitive functions (attention, memory, executive functions and reasoning) and psychological well-being (PWB). A single-blind randomized controlled trial was conducted in adult day care centres in Helsinki, Finland. Participants (N = 147) were older individuals with mild to moderate dementia living at home and attending day care (mean age 83 years, 72% female, 63% at mild stage of dementia). The intervention group (n = 76) received systematic CT for 45 min twice a week while the control group (n = 71) attended day care as usual. The cognitive and psychological outcomes were measured at baseline, and followed up at 3 and 9 months. No differences between the two groups in changes of any of the cognitive functions, or PWB over time were found. We observed a positive trend at 3 months in the change for PWB favouring the intervention group, but no significant interaction effect was found (p = .079; d = -0.31). Thus, systematic CT appears to have no effect on neuropsychological outcomes of cognitive functioning and PWB in older adults who already have dementia.

中文翻译：

---

轻度至中度痴呆认知训练的神经心理学结果：一项随机对照试验

对社区痴呆患者进行的为期 12 周的认知训练 (CT) 计划的有效性在各种认知功能（注意力、记忆力、执行功能和推理）和心理健康 (PWB) 方面进行了评估。在芬兰赫尔辛基的成人日托中心进行了一项单盲随机对照试验。参与者（N = 147）是患有轻度至中度痴呆症的老年人，住在家里并参加日托（平均年龄 83 岁，72% 女性，63% 处于轻度痴呆症阶段）。干预组 (n = 76) 每周两次接受系统 CT 45 分钟，而对照组 (n = 71) 照常参加日托。在基线时测量认知和心理结果，并在 3 个月和 9 个月时进行随访。两组在任何认知功能的变化上没有差异，或 PWB 随着时间的推移被发现。我们在 3 个月时观察到 PWB 的变化有利于干预组的积极趋势，但没有发现显着的交互作用（p = .079；d = -0.31）。因此，系统 CT 似乎对已经患有痴呆症的老年人的认知功能和 PWB 的神经心理学结果没有影响。