Momordica charantia is a medicinal plant which is widely used in different traditional medicinal systems to treat several diseases. We have identified the differential distribution of phytomedicinally important metabolites in the pericarp, skin and seeds of M. charantia fruit via NMR spectroscopy. Multivariate statistical analysis showed a clustering of the metabolic profiles of seeds and pericarp, and their clear separation from the metabolic profile of the skin. The total phenolic and flavonoid content of the fruit extracts were estimated via bioassays, the radical scavenging activity was estimated via in vitro DPPH and ABTS assays and an inhibitory activity test of α-glucosidase was also performed. The pericarp and seeds contained significant amounts of phenolic compounds and flavonoids, indicating that they are a good source for antioxidants. The skin contained a significantly higher amount of phytosterols such as Charantin and momordicine, which are known to correlate with antidiabetic activity.

苦瓜是一种药用植物，广泛用于不同的传统医学系统中以治疗多种疾病。我们已经通过核磁共振波谱法鉴定了药用植物重要代谢产物在苦瓜果实的果皮，皮肤和种子中的差异分布。多变量统计分析表明，种子和果皮的代谢谱聚类，并且它们与皮肤的代谢谱清楚分离。通过生物测定法评估水果提取物中的总酚和类黄酮含量，通过体外DPPH和ABTS测定法以及α的抑制活性测试评估自由基清除活性-葡糖苷酶也被执行。果皮和种子中含有大量的酚类化合物和类黄酮，表明它们是抗氧化剂的良好来源。皮肤中含有大量的植物甾醇，例如Charantin和莫莫地辛，它们与抗糖尿病活性有关。