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Evaluation of various biological activities of natural compounds by TLC/HPTLC
Journal of Liquid Chromatography & Related Technologies ( IF 1.3 ) Pub Date : 2020-02-17 , DOI: 10.1080/10826076.2020.1725548
Anamaria Hosu 1 , Claudia Cimpoiu 1
Affiliation  

Abstract Over the last years, thin layer chromatography (TLC) has become an increasingly important tool in the analysis of natural compounds, being used not only as a simple method of separation, identification, and quantitative determination of natural constituents, but also as a method for evaluating the potential applications of the separated compounds, different bioassays being compatible with TLC. This is due to the TLC advantages, of which could be mentioned: the possibility to simply, quickly, and flexibly analyze many samples in parallel, without the need for special steps of sample purification, obtaining visual results, and the possibility of multiple detections, all of these being achieved at very low costs. Considering these, the aim of this study is to give an overview on the application of TLC in evaluation of different biological activities of natural compounds, focusing on antioxidant, enzymatic, antimicrobial, and hormonal activities. GRAPHICAL ABSTRACT

中文翻译:

TLC/HPTLC评价天然化合物的各种生物活性

摘要 近年来,薄层色谱 (TLC) 已成为天然化合物分析中日益重要的工具,不仅用作分离、鉴定和定量测定天然成分的简单方法,而且作为一种方法用于评估分离化合物的潜在应用,不同的生物测定与 TLC 兼容。这是由于TLC的优点,其中可以提到:可以简单、快速、灵活地并行分析许多样品,无需样品纯化的特殊步骤,获得视觉结果,以及多次检测的可能性,所有这些都是以非常低的成本实现的。考虑到这些,本研究的目的是概述薄层色谱在评估天然化合物不同生物活性中的应用,重点是抗氧化、酶促、抗菌和激素活性。图形概要
更新日期:2020-02-17
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