ABSTRACT The Phlomis kurdica Rech.fil. (Lamiaceae) essential oil was investigated for its chemical constituents and in vitro biological activities. Volatile components were characterized, antimicrobial and anticholinesterase activities were performed. The oil was analyzed both by gas chromatography-mass spectrometry and gas chromatography-flame ionization detector, simultaneously. The in vitro antimicrobial microdilution method was used against Bacillus cereus ATCC 14579, Pseudomonas aeruginosa ATCC 10145, Escherichia coli NRLL B-3008, Staphylococcus aureus ATCC 6538, Helicobacter pylori ATCC 43504, Staphylococcus epidermidis ATCC 14990, and Candida albicans ATCC 90028, respectively. Additionally, the cholinesterase enzyme inhibition activities were tested in vitro using the Ellman method. A total of forty-four different volatile constituents were identified, where the main components were characterized as germacrene D (55.4%), (Z)-β-farnesene (11.2%), and hexadecanoic acid (8.4%), respectively. The P. kurdica oil showed moderate inhibition of cholinesterases, where inhibitory antimicrobial activity was against B. cereus among the tested microorganisms.

中文翻译：

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精油 Phlomis kurdica Rech 的抗菌、抗胆碱酯酶评估和化学表征。菲尔。在土耳其成长

摘要 Phlomis kurdica Rech.fil。对（唇形科）精油的化学成分和体外生物活性进行了研究。表征挥发性成分，进行抗微生物和抗胆碱酯酶活性。同时通过气相色谱-质谱和气相色谱-火焰离子化检测器对油进行分析。体外抗菌微量稀释法分别对蜡样芽孢杆菌ATCC 14579、铜绿假单胞菌ATCC 10145、大肠杆菌NRLL B-3008、金黄色葡萄球菌ATCC 6538、幽门螺杆菌ATCC 43504、葡萄球菌ATCC 43504、葡萄球菌ATCC 43504、表皮葡萄球菌ATCC20101和表皮葡萄球菌2018CC。此外，胆碱酯酶抑制活性在体外使用 Ellman 方法进行了测试。共鉴定出 44 种不同的挥发性成分，其中主要成分分别为锗烯 D (55.4%)、(Z)-β-法呢烯 (11.2%) 和十六烷酸 (8.4%)。P. kurdica 油显示出对胆碱酯酶的中度抑制，其中抑制性抗菌活性是针对测试微生物中的蜡状芽孢杆菌。