Abstract Three silver(I) complex compounds of halogen derivatives of 8-quinolinol (XQ), [Ag(HdClQ)2](NO3)·CH3OH (1), [Ag(HdBrQ)2](NO3) (2), and [Ag(BrQ)]n (3) (HdClQ = 5,7-dichloro-8-quinolinol, HdBrQ = 5,7-dibromo-8-quinolinol, and HBrQ = 7-bromo-8-quinolinol), have been prepared with the aim to study their anticancer properties. All compounds were characterized by IR and NMR spectroscopy and elemental analysis. Single-crystal X-ray diffraction analysis revealed that crystal structure of 1 is ionic, 2 is molecular while 3 is polymeric. All three XQ ligands in 1–3 are N,O-chelate coordinated to the Ag(I) central atoms which are in a deformed square planar (1), distorted tetragonal pyramidal (2), or distorted triangular arrangement (3). Stability of all compounds in DMSO was proved by 1H NMR and UV-vis spectroscopy. Biological activity has not been studied because of limited solubility of prepared compounds in DMSO/water mixture. Graphical Abstract

中文翻译：

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羟基喹啉基银 (I) 配合物的合成、溶液稳定性和结构表征

摘要 8-羟基喹啉(XQ)、[Ag(HdClQ)2](NO3)·CH3OH(1)、[Ag(HdBrQ)2](NO3)(2)和[Ag(BrQ)]n (3) (HdClQ = 5,7-dichloro-8-quinolinol, HdBrQ = 5,7-dibromo-8-quinolinol, and HBrQ = 7-bromo-8-quinolinol), 已制备目的是研究它们的抗癌特性。所有化合物均通过 IR 和 NMR 光谱以及元素分析进行​​表征。单晶 X 射线衍射分析表明，1 的晶体结构是离子型，2 是分子型，而 3 是聚合物型。1-3 中的所有三个 XQ 配体都是与 Ag(I) 中心原子配位的 N,O-螯合物，这些原子处于变形的方形平面 (1)、扭曲的四方锥体 (2) 或扭曲的三角形排列 (3) 中。所有化合物在 DMSO 中的稳定性均通过 1H NMR 和 UV-vis 光谱证明。由于制备的化合物在 DMSO/水混合物中的溶解度有限，因此尚未研究生物活性。图形概要