Generating feelings of satiety may be important in maintaining weight control. It has been hypothesised that the circulating concentration of glucose is a major determinant of satiety, yet the relationship between postprandial glycaemia and satiety is inconclusive. Our aim was to assess satiety following ingestion of beverages differing in glycaemic index (GI) containing either 50 g of sucrose (GI 65) or isomaltulose (PalatinoseTM) (GI 32). The beverages were matched for sweetness using a triangle sensory test. Seventy-seven participants were randomised to the order in which they received each beverage, 2 weeks apart. A standard lunch was given at 12.00 hours. Satiety was measured using 100-mm visual analogue scales (VAS) administered at 14.00 hours (baseline) and at 30, 60, 90, 120, 150 and 180 min after ingesting the beverage. Weighed diet records were kept from 17.00 to 24.00 hours. Mean differences for isomaltulose compared with sucrose AUC VAS were ‘How hungry do you feel?’ 109 (95 % CI –443, 661) mm × min; ‘How satisfied do you feel?’ 29 (95 % CI –569, 627) mm × min; ‘How full do you feel?’ −91 (95 % CI –725, 544) mm × min and ‘How much do you think you can eat?’ 300 (95 % CI –318, 919) mm × min. There was no between-treatment difference in satiety question responses or in dietary energy intake −291 (95 % CI −845, 267) kJ over the remainder of the day. In this experiment, feelings of satiety were independent of the GI of the test beverages. Any differences in satiety found between foods chosen on the basis of GI could be attributable to food properties other than the glycaemic-inducing potential of the food.

中文翻译：

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摄入等甜和等能量蔗糖和异麦芽酮糖甜饮料对饱腹感的影响：一项随机交叉试验

产生饱腹感对于维持体重控制可能很重要。据推测，循环葡萄糖浓度是饱腹感的主要决定因素，但餐后血糖与饱腹感之间的关系尚无定论。我们的目的是评估摄入含有 50 克蔗糖 (GI 65) 或异麦芽酮糖 (Palatinose) 的血糖指数 (GI) 不同的饮料后的饱腹感TM值) (GI 32)。使用三角感官测试匹配饮料的甜度。77 名参与者被随机分配到他们接受每种饮料的顺序，相隔 2 周。中午 12:00 提供标准午餐。饱腹感使用 100 毫米视觉模拟量表 (VAS) 在 14.00 小时（基线）和摄入饮料后 30、60、90、120、150 和 180 分钟时进行测量。称重的饮食记录从 17.00 到 24.00 小时保存。与蔗糖 AUC VAS 相比，异麦芽酮糖的平均差异是“你感觉有多饿？” 109 (95 % CI –443, 661) 毫米 × 分钟；“你觉得满意吗？” 29 (95 % CI –569, 627) 毫米 × 分钟；“你感觉有多饱？” −91 (95 % CI –725, 544) mm × min 和“你认为你能吃多少？” 300 (95 % CI –318, 919) 毫米 × 分钟。在一天的剩余时间里，饱腹感问题反应或饮食能量摄入 -291 (95 % CI -845, 267) kJ 之间没有治疗差异。在这个实验中，饱腹感与测试饮料的 GI 无关。在基于 GI 选择的食物之间发现的任何饱腹感差异都可能归因于食物的特性，而不是食物的血糖诱导潜力。