ABSTRACT

The anterior temporal lobe (ATL) is considered a crucial area for the representation of transmodal concepts. Recent evidence suggests that specific regions within the ATL support the representation of individual object concepts, as shown by studies combining multivariate analysis methods and explicit measures of semantic knowledge. This research looks to further our understanding by probing conceptual representations at a spatially and temporally resolved neural scale. Representational similarity analysis was applied to human intracranial recordings from anatomically defined lateral to medial ATL sub-regions. Neural similarity patterns were tested against semantic similarity measures, where semantic similarity was defined by a hybrid corpus-based and feature-based approach. Analyses show that the perirhinal cortex, in the medial ATL, significantly related to semantic effects around 200 to 400 ms, and were greater than more lateral ATL regions. Further, semantic effects were present in low frequency (theta and alpha) oscillatory phase signals. These results provide converging support that more medial regions of the ATL support the representation of basic-level visual object concepts within the first 400 ms, and provide a bridge between prior fMRI and MEG work by offering detailed evidence for the presence of conceptual representations within the ATL.

摘要

前颞叶（ATL）被认为是跨模式概念表示的关键领域。最近的证据表明，ATL中的特定区域支持单个对象概念的表示，如结合多变量分析方法和语义知识的显式度量的研究所示。这项研究通过在空间和时间上解析的神经尺度上探究概念表示来寻求进一步的理解。代表性相似性分析应用于从解剖学上定义的外侧到内侧ATL子区域的人类颅内记录。针对语义相似性度量测试了神经相似性模式，其中语义相似性是通过基于混合语料库和基于特征的方法定义的。分析表明，内侧ATL中的周围神经皮层 与200到400毫秒左右的语义效果显着相关，并且大于更多的横向ATL区域。此外，语义效应存在于低频（θ和α）振荡相位信号中。这些结果提供了收敛的支持，即ATL的更多中间区域在前400毫秒内支持基本级视觉对象概念的表示，并通过提供详细的证据来证明ATL中存在概念表示，从而在先前的fMRI和MEG工作之间架起了桥梁。 ATL。