This study was designed to examine the effect of almond‐included diets on sexual behavior, arginase activity, and pro‐inflammatory markers in diabetic male rats. Forty‐two male rats were divided into seven groups (n = 6). Diabetes was triggered via a single dose intraperitoneal injection of streptozotocin (50 mg/kg). Diabetes was confirmed 72 hr after STZ induction, and animals with blood glucose ≥ 250 mg/dl were considered diabetic and used for the experiment. The effects of almond‐supplemented diets on glucose level, sexual function, NF‐κB and TNF‐α levels, arginase and purinergic enzyme activities, and levels of oxidative stress markers were assessed. A significant decrease in sexual activities with a simultaneous increase in pro‐inflammatory markers, arginase and purinergic enzyme activities as well as TBARS and ROS levels was observed in diabetic rats. Interestingly, treatment with supplemented diets ameliorated the effects. Conclusively, intake of almonds could prevent the risk of erectile dysfunction in diabetic subjects.

中文翻译：

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饮食中添加杏仁水果对糖尿病雄性大鼠性行为，精氨酸酶活性，促炎和氧化应激指标的影响

本研究旨在检查杏仁饮食对糖尿病雄性大鼠性行为，精氨酸酶活性和促炎性标志物的影响。将42只雄性大鼠分为7组（n = 6）。腹膜内注射单剂量链脲佐菌素（50 mg / kg）可触发糖尿病。诱导STZ后72小时确认为糖尿病，血糖≥250 mg / dl的动物被认为患有糖尿病，并用于实验。评估了杏仁补充饮食对葡萄糖水平，性功能，NF-κB和TNF-α水平，精氨酸酶和嘌呤能酶活性以及氧化应激标志物水平的影响。在糖尿病大鼠中，观察到性活动显着减少，同时促炎性标志物，精氨酸酶和嘌呤能酶活性以及TBARS和ROS水平同时增加。有趣的是，补充饮食可以改善这种效果。结论是，摄入杏仁可以预防糖尿病患者发生勃起功能障碍的风险。