HLA antibody repertoire in infants suggests selectivity in transplacental crossing.,American Journal of Reproductive Immunology

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HLA antibody repertoire in infants suggests selectivity in transplacental crossing.
American Journal of Reproductive Immunology ( IF 3.6 ) Pub Date : 2020-05-12 , DOI: 10.1111/aji.13264
Dana M Savulescu ₁ , Michelle Groome _{2,

3} , Susan C K Malfeld ₁ , Shabir Madhi _{2,

3} , Anthonet Koen _{2,

3} , Stephanie Jones _{2,

3} , Vania Duxbury ₄ , Karine Scheuermaier ₄ , Debbie De Assis Rosa ₅ , Melinda Suchard _{1,

6}

Affiliation

Late in pregnancy, women produce and transfer high amounts of antibodies to the foetus. During gestation, women produce antibodies against human leukocyte antigens (HLA), including antibodies directed at foetal HLA. There is paucity of data on transplacental crossing, specificity and role of HLA antibodies in pregnancy and new‐borns.

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