Partial fluorination of graphene is known to enhance its heterogeneous electron transfer (HET) rates with a significant impact on its application as electrochemical sensors. However, the results had been rather inconclusive on the correlation between the HET rates and the degree of fluorine coverage. We address this using a top-down approach, via the step-wise defluorination of fluorographene using the solvent-assisted, sonochemical method. The results suggest that in addition to the fluorine coverage, the structural and morphological features also have a significant role in governing the HET rates. The reversible limit of HET is attained in the case of glassy carbon electrode modified with partially defluorinated fluorographene with 26% of fluorine coverage studied with the redox probe [Fe(CN)₆]^4−/3−, and this is correlated to the formation of the unique onion-like interconnected nanocarbon structural features. Electrochemical sensing studies with the prepared fluorographene systems using some important biomarkers like ascorbic acid (AA), uric acid (UA) and dopamine (DA) are also reported.

已知石墨烯的部分氟化会提高其异质电子转移（HET）速率，并对其在电化学传感器中的应用产生重大影响。但是，关于HET速率与氟覆盖程度之间的相关性，结果尚无定论。我们使用自顶向下的方法，通过使用溶剂辅助的声化学方法对氟石墨烯进行逐步脱氟处理。结果表明，除氟覆盖外，结构和形态特征在控制HET速率方面也起着重要作用。在用氧化还原探针[Fe（CN）₆研究的部分脱氟化氟石墨烯修饰了26％的氟覆盖率的玻碳电极上，达到了HET的可逆极限。] ^{4− / 3-−}，这与独特的洋葱状互连纳米碳结构特征的形成有关。还报道了使用一些重要的生物标志物，如抗坏血酸（AA），尿酸（UA）和多巴胺（DA），对制备的氟石墨烯系统进行的电化学传感研究。