OBJECTIVES This meta-analysis aimed to (1) quantitatively synthesize evidence of factors related to the quality of life (QoL) of family carers of people with dementia and (2) explore moderating factors that may influence the strength of the relationship between such potential predictive factors and carer QoL. METHODS Studies that investigated correlations between patient/carer factors and QoL in unpaid family carers of people with dementia and were published in English, Spanish, Portuguese, or Japanese were included. RESULTS Thirty-three studies were identified. The pooled correlations with carer QoL (effect size) were significantly large for depression (-0.58), significantly moderate for subjective burden (-0.47), and significantly small for people with dementia's neuropsychiatric symptoms (-0.24). These results indicated to be robust in the context of publication bias. The results of subgroup analyses demonstrated the social and economic development status of the country where study participants resided did not moderate these effects. CONCLUSION Carer depression, subjective burden, and people with dementia's neuropsychiatric symptoms may play a critical role in maintaining QoL of family carers regardless of the social and economic circumstances.

中文翻译：

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与痴呆症患者家庭照顾者生活质量相关的因素：元分析。

目标 本荟萃分析旨在 (1) 定量综合与痴呆症患者家庭照顾者的生活质量 (QoL) 相关因素的证据，以及 (2) 探索可能影响此类潜在预测因素之间关系强度的调节因素。因素和照顾者 QoL。方法 研究调查了痴呆症患者的无偿家庭照顾者的患者/照顾者因素与 QoL 之间的相关性，并以英语、西班牙语、葡萄牙语或日语发表。结果 确定了 33 项研究。与照顾者 QoL（效应量）的汇总相关性对于抑郁症显着较大 (-0.58)，对于主观负担显着中等 (-0.47)，对于患有痴呆症神经精神症状的人来说显着较小 (-0.24)。这些结果表明在发表偏倚的情况下是稳健的。亚组分析的结果表明，研究参与者所在国家的社会和经济发展状况并未减轻这些影响。结论无论社会和经济环境如何，照顾者的抑郁、主观负担和痴呆症患者的神经精神症状可能在维持家庭照顾者的 QoL 中发挥关键作用。