Abstract—

Hydrogen peroxide, one of the main factors of Mycoplasma pneumoniae pathogenicity, is released in the reaction catalyzed by glycerol-3-phosphate (G3P) oxidase enzyme (EC 1.1.3.21). During the study, nucleotide substitutions in the glycerol-3-phosphate oxidase gene of Mycoplasma pneumoniae clinical isolates, the presence of which was accompanied by different levels of hydrogen peroxide production and cytotoxicity of Mycoplasma pneumoniae isolates regarding respiratory epithelial cells, were detected.

中文翻译：

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甘油3-磷酸氧化酶基因的核苷酸取代，过氧化氢产生水平和肺炎支原体细胞毒性之间的相关性

摘要-

过氧化氢是肺炎支原体致病性的主要因素之一，在3-磷酸甘油（G3P）氧化酶（EC 1.1.3.21）催化的反应中释放。在研究过程中，检测到肺炎支原体临床分离株的甘油3-磷酸氧化酶基因中的核苷酸取代，并伴随着不同水平的过氧化氢生成和肺炎支原体分离株对呼吸道上皮细胞的细胞毒性。