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ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection.
bioRxiv - Pathology Pub Date : 2020-05-09 , DOI: 10.1101/2020.05.09.086165
Lingli Zhou , Zhenhua Xu , Gianni M. Castiglione , Uri S. Soiberman , Charles G. Eberhart , Elia J. Duh

Purpose Conjunctival signs and symptoms are observed in a subset of patients with COVID-19, and SARS-CoV-2 has been detected in tears, raising concerns regarding the eye both as a portal of entry and carrier of the virus. The purpose of this study was to determine whether ocular surface cells possess the key factors required for cellular susceptibility to SARS-CoV-2 entry/infection.

中文翻译:

ACE2 和 TMPRSS2 在人眼表面表达,表明对 SARS-CoV-2 感染的易感性。

目的在一部分 COVID-19 患者中观察到结膜体征和症状,并且在眼泪中检测到 SARS-CoV-2,这引起了人们对眼睛作为病毒进入和携带者的关注。本研究的目的是确定眼表细胞是否具有细胞对 SARS-CoV-2 进入/感染的易感性所需的关键因素。
更新日期:2020-05-09
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