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Searching for new long-term urinary metabolites of metenolone and drostanolone using gas chromatography-mass spectrometry with a focus on non-hydrolysed sulfates.
Drug Testing and Analysis ( IF 2.9 ) Pub Date : 2020-07-13 , DOI: 10.1002/dta.2818
Aðalheiður Dóra Albertsdóttir 1 , Wim Van Gansbeke 1 , Gilles Coppieters 1 , Kyzylkul Balgimbekova 2 , Peter Van Eenoo 1 , Michael Polet 1
Affiliation  

Sulfated metabolites have been shown to have potential as long‐term markers of anabolic–androgenic steroid (AAS) abuse. In 2019, the compatibility of gas chromatography–mass spectrometry (GC–MS) with non‐hydrolysed sulfated steroids was demonstrated, and this approach allowed the incorporation of these compounds in a broad GC–MS initial testing procedure at a later stage. However, research is needed to identify which are beneficial.

中文翻译:

使用气相色谱-质谱法,重点研究非水解硫酸盐,寻找美替龙和丁烯诺酮的新的长期尿代谢产物。

硫酸盐代谢物已被证明是长期合成代谢-雄激素类固醇(AAS)的标志物。在2019年,证明了气相色谱-质谱法(GC-MS)与未水解的硫酸化类固醇的相容性,并且这种方法允许在以后的阶段将这些化合物纳入广泛的GC-MS初始测试程序中。但是,需要进行研究以确定哪些是有益的。
更新日期:2020-07-13
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