Progenitor cells mobilized by granulocyte colony-stimulating factor (G-CSF) have been shown to lessen acute kidney injury induced by extracorporeal circulation (ECC). Both acute kidney injury and lung injury are characterized by endothelial dysfunction. Our goal was to examine whether and how G-CSF-mobilized progenitors with endothelial capacity may help mitigate ECC-induced pulmonary dysfunction.

中文翻译：

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CD133 +祖细胞的预动与小鼠体外循环后炎症减轻引起的肺功能障碍有关。

已显示由粒细胞集落刺激因子（G-CSF）动员的祖细胞可减轻体外循环（ECC）诱导的急性肾脏损伤。急性肾损伤和肺损伤均以内皮功能障碍为特征。我们的目标是研究具有内皮功能的G-CSF动员的祖细胞是否以及如何帮助减轻ECC引起的肺功能障碍。