Background: In this study it is evaluated whether autogenous bone mixed with biphasic calcium phosphate (BCP) used in a maxillary sinus floor elevation (MSFE) leads to improved bone formation. Materials and methods: In five patients a unilateral MSFE was performed. Histological and histomorphometric analyses were performed on bone biopsies that were obtained 6 months after MSFE during dental implant surgery. Results: The average vital bone volume was 29.9% of the total biopsy (BV/TV, SD ± 10.1) of which 7.1% was osteoid (OV/BV, SD ± 4.8). The osteoid surface (OS/BS) covered 26.0% (SD ± 13.4) of the bone surface. The BS/TV covered 4.7 mm²/mm³ (SD ± 2.3). Compared with previous studies the analyses showed a difference for trabecular thickness (Tb.Th.) and osteoid surface (OS/BS), but not for BV/TV, OV/BV and the number of osteoclasts. Conclusion: MSFE with autogenous bone mixed with BCP shows an amount of newly formed bone that is comparable with the findings from the previously published 6-month study with pure BCP. However, a better distribution of the new bone over the entire biopsy was observed.

中文翻译：

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自体骨与双相磷酸钙混合在上颌窦底提升手术中使用，愈合时间为6个月：临床，放射学，组织学和组织形态学评估

背景：在这项研究中，评估了用于上颌窦底抬高（MSFE）的自体骨与双相磷酸钙（BCP）混合是否能改善骨形成。材料和方法：在五名患者中进行了单侧MSFE。对在牙科植入手术中MSFE术后6个月获得的骨活检进行组织学和组织形态计量学分析。结果：平均活骨量占活检总人数的29.9％（BV / TV，SD±10.1），其中有7.1％为类骨质骨（OV / BV，SD±4.8）。类骨质表面（OS / BS）覆盖了骨表面的26.0％（SD±13.4）。BS / TV覆盖4.7 mm ² / mm ³（SD±2.3）。与以前的研究相比，分析显示小梁厚度（Tb.Th.）和类骨质表面（OS / BS）有所不同，但BV / TV，OV / BV和破骨细胞的数量没有差异。结论：MSFE的自体骨与BCP混合显示新形成的骨量与先前发表的为期6个月的纯BCP研究结果相当。然而，观察到新骨在整个活检组织中的分布更好。