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Randomized, controlled, participant- and rater-blind trial of pharmacogenomic test-guided treatment versus treatment as usual for major depressive disorder.
Depression and Anxiety ( IF 7.4 ) Pub Date : 2020-05-07 , DOI: 10.1002/da.23029
Roy H Perlis 1 , Daniel Dowd 2 , Maurizio Fava 1 , Todd Lencz 3 , David S Krause 2
Affiliation  

Cohort and cost‐effectiveness studies suggest that measuring variation in genes that influence metabolism of common drugs could improve antidepressant treatment outcomes. Prior randomized trials have yielded inconsistent results.

中文翻译:

药物基因组学测试指导治疗与一般抑郁症治疗的随机,对照,参与者和评估者盲试验。

队列研究和成本效益研究表明,测量影响普通药物代谢的基因变异可以改善抗抑郁药的治疗效果。先前的随机试验得出的结果不一致。
更新日期:2020-05-07
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