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Altered protein levels in bone marrow lesions of hip osteoarthritis: Analysis by proteomics and multiplex immunoassays.
International Journal of Rheumatic Diseases ( IF 2.5 ) Pub Date : 2020-05-07 , DOI: 10.1111/1756-185x.13843
Maziar Shabestari 1 , Yashar R Shabestari 1 , Maria A Landin 1 , Milaim Pepaj 2 , Timothy P Cleland 3 , Janne E Reseland 1 , Erik F Eriksen 4, 5
Affiliation  

To assess tissue level changes of proteome and cytokine profiles of subchondral bone in hip osteoarthritis (OA) affected by bone marrow lesions (BMLs). We compared significant protein level differences in osteoarthritic bone with BMLs to control bone without bone marrow lesions.

中文翻译:

髋骨关节炎骨髓病变中蛋白质水平的改变:通过蛋白质组学和多重免疫分析法进行分析。

评估受骨髓损伤(BML)影响的髋骨关节炎(OA)中软骨下骨的蛋白质组和细胞因子分布的组织水平变化。我们比较了使用BML的骨关节炎骨中明显的蛋白质水平差异,以控制无骨髓病变的骨。
更新日期:2020-06-23
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