Introduction: Since the emergence of Candida auris infection in 2009, the disease has been reported from multiple countries within a decade. The infection is classified under urgent threat, as it is multi-drug resistant, causes high mortality, spreads easily in hospital setting and is difficult to identify. Whole-genome sequencing has provided insights into this organisms biology and epidemiology. A comprehensive review of those issues would help the clinicians and scientists facing C. auris infection.Areas covered: We reviewed the epidemiological trends of C. auris infection, including the genomic epidemiology based on an electronic search using Pubmed and Google scholar. We also discuss the biology, virulence attributes of this pathogen, its clinical presentations and associated risk factors. The mechanisms of antifungal resistance known so far are also described in addition to factors involved in the nosocomial transmission, environmental survival and ecology of C. auris.Expert opinion: Despite the attention of multiple researchers evaluating every aspect of this organism and its epidemiology, there are several gaps in tracing its origin and understanding the dynamics of nosocomial transmission and global spread. Multidisciplinary, coordinated studies are required to understand the biology, ecology, method of survival and spread of the organism in healthcare setup.

中文翻译：

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多药耐药念珠菌：流行病学评论。

简介：自2009年出现假性念珠菌感染以来，十年来已有多个国家报告该病。该感染被归类为紧急威胁，因为它具有多重耐药性，可导致高死亡率，在医院中容易传播且难以识别。全基因组测序提供了对该生物生物学和流行病学的见识。对这些问题的全面回顾将有助于临床医生和科学家面对金黄色葡萄球菌感染。研究领域包括：我们审查了金黄色葡萄球菌感染的流行病学趋势，包括基于基因组流行病学的电子流行病学，使用Pubmed和Google Scholar。我们还将讨论该病原体的生物学，毒力属性，其临床表现和相关的危险因素。除了涉及真菌传播，环境存活和耳形衣藻的因素外，到目前为止还描述了迄今为止已知的抗真菌抗药性的机制。专家意见：尽管有许多研究人员对这种微生物及其流行病学的各个方面进行了关注，在追踪其起源和了解医院传播和全球传播的动态方面存在几个空白。需要进行多学科，协调的研究，以了解医疗机构中生物的生物学，生态学，生存方法和传播方式。在追踪其起源和了解医院传播和全球传播的动态方面存在一些差距。需要进行多学科，协调的研究，以了解医疗机构中生物的生物学，生态学，生存方法和传播方式。在追踪其起源和了解医院传播和全球传播的动态方面存在一些差距。需要进行多学科，协调的研究，以了解医疗机构中生物的生物学，生态学，生存方法和传播方式。