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Preventing catheter-related infections in cancer patients: a review of current strategies.
Expert Review of Anti-infective Therapy ( IF 5.7 ) Pub Date : 2020-04-12 , DOI: 10.1080/14787210.2020.1750367
Alexandre E Malek 1 , Issam I Raad 1
Affiliation  

Introduction: Central line-associated bloodstream infections (CLABSI) are a frequent cause of healthcare-associated infections, increasing healthcare costs and decreasing the quality of life for critically and chronically ill patients such as those with cancer. These infections are largely preventable and have been significantly reduced throughout the United States. However, further reduction of CLABSI requires continued innovation in preventive strategies.Areas covered: We provide an overview of the recent medical literature on catheter-related infections among cancer patients, discussing epidemiology, risk factors, and pathogenesis of CLABSI with a focus on the newest and current preventive measures. The data discussed here were retrieved mainly from clinical trials, meta-analyses, and systematic reviews published in the English language using a MEDLINE database search from 1 January 1990 until the end of December 2019.Expert opinion: The growing impact of CLABSI on the healthcare setting and mortality and morbidity rates in cancer patients calls for novel technologies for preventing central line-related infections. Advances in antimicrobial lock therapy are not limited to salvage therapy but have also provided a novel and promising prophylactic approach to CLABSI. Also, the use of antimicrobial-coated catheters with chlorhexidine-impregnated dressings, along with the application of insertion and maintenance bundles, is an effective and cost-effective approach for preventing central line-related infections.

中文翻译:

预防癌症患者的导管相关感染:当前策略的综述。

简介:中枢线相关的血液感染(CLABSI)是医疗保健相关感染的常见原因,增加了医疗保健成本并降低了重症和慢性病患者(如癌症患者)的生活质量。这些感染在很大程度上是可以预防的,并且在整个美国已大大减少。然而,进一步降低CLABSI需要在预防策略上进行持续创新。涵盖的领域:我们概述了癌症患者中导管相关感染的最新医学文献,讨论了CLABSI的流行病学,危险因素和发病机理,重点是最新的和当前的预防措施。这里讨论的数据主要来自临床试验,荟萃分析,1990年1月1日至2019年12月末使用MEDLINE数据库搜索以英文发表的系统评价和系统评价。专家意见:CLABSI对癌症患者的医疗保健条件,死亡率和发病率的影响越来越大,因此需要新颖的预防方法中线相关感染。抗菌锁定治疗的进展不仅限于抢救疗法,还为CLABSI提供了一种新颖而有希望的预防方法。同样,将抗菌涂层的导管与洗必泰浸渍的敷料一起使用,以及插入和维持束的应用,是预防中心线相关感染的有效且具有成本效益的方法。CLABSI对癌症患者的医疗机构以及死亡率和发病率的影响越来越大,因此需要预防中心线相关感染的新技术。抗菌锁定治疗的进展不仅限于抢救疗法,还为CLABSI提供了一种新颖而有希望的预防方法。同样,将抗菌涂层的导管与洗必泰浸渍的敷料一起使用,以及插入和维持束的应用,是预防中心线相关感染的有效且具有成本效益的方法。CLABSI对癌症患者的医疗机构以及死亡率和发病率的影响越来越大,因此需要预防中心线相关感染的新技术。抗菌锁定治疗的进展不仅限于抢救疗法,还为CLABSI提供了一种新颖而有希望的预防方法。同样,将抗菌涂层的导管与洗必泰浸渍的敷料一起使用,以及插入和维持束的应用,是预防中心线相关感染的有效且具有成本效益的方法。抗菌锁定治疗的进展不仅限于抢救疗法,还为CLABSI提供了一种新颖而有希望的预防方法。同样,将抗菌涂层的导管与洗必泰浸渍的敷料一起使用,以及插入和维持束的应用,是预防中心线相关感染的有效且具有成本效益的方法。抗菌锁定治疗的进展不仅限于抢救疗法,还为CLABSI提供了一种新颖而有希望的预防方法。同样,将抗菌涂层的导管与洗必泰浸渍的敷料一起使用,以及插入和维持束的应用,是预防中心线相关感染的有效且具有成本效益的方法。
更新日期:2020-04-12
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