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Effect of Urtica dioica (nettle) on quality of sleep in hemodialysis patients: A randomized clinical trial
Journal of Herbal Medicine ( IF 2.3 ) Pub Date : 2020-05-08 , DOI: 10.1016/j.hermed.2020.100356
Khadijeh Alizadeh , Ravanbakhsh Esmaeili , Seyed Afshin Shorofi , Nouraddin Mousavinasab , Fatemeh Espahbodi , Mousa Esmaeili

Background

Sleep disorders are common in patients with end-stage renal disease. The present study aimed to examine the effect of (Nettle) on sleep quality in hemodialysis patients.

Materials and Methods

: This randomized clinical trial was conducted on 90 hemodialysis patients. Using the convenience sampling method, the participants were selected and then randomly assigned to intervention and control groups. The intervention group was provided with 400-mg Urtica dioica tablets three times a day for three consecutive months. On the other hand, the control group did not receive any intervention. The socio-demographic/ clinical characteristics were collected using a pre-structured questionnaire. Sleep quality was assessed using the Pittsburgh Sleep Quality Index before the intervention and after the first, second, and third months of intervention.

Results

The results of the study were indicative of no statistically significant difference between the two groups in terms of sleep quality before and after the intervention (P = 0.09). Moreover, the effect ofUrtica dioica on sleep quality was not significantly different at the end of the first (P = 0.14), second (P = 0.34), and third (P = 0.97) months.

Conclusion

As evidenced by the obtained results,Urtica dioica did not significantly improve sleep quality in hemodialysis patients. Despite the use of hypnotics, poor sleep quality is common among hemodialysis patients. Nonetheless, Urtica dioica along with hypnotics helped maintain the stability of sleep quality in the present study. Urtica dioica tablets in the hemodialysis patients decreased sleep latency and increased sleep duration.



中文翻译:

的影响大荨麻对血液透析患者睡眠质量(荨麻):一项随机临床试验

背景

睡眠障碍在终末期肾病患者中很常见。本研究旨在检查(荨麻)对血液透析患者睡眠质量的影响。

材料和方法

:这项随机临床试验是针对 90 名血液透析患者进行的。使用便利抽样方法,选择参与者,然后随机分配到干预组和对照组。干预组连续三个月每天服用3 次400 毫克荨麻片。另一方面,对照组没有接受任何干预。社会人口统计/临床特征是使用预先结构化的问卷收集的。在干预前和干预的第一、第二和第三个月之后,使用匹兹堡睡眠质量指数评估睡眠质量。

结果

研究结果表明,两组在干预前后的睡眠质量方面无统计学差异(P = 0.09)。此外,荨麻对睡眠质量的影响在第一个月 (P = 0.14)、第二个月 (P = 0.34) 和第三个月 (P = 0.97) 结束时没有显着差异。

结论

所获得的结果证明,荨麻并没有显着改善血液透析患者的睡眠质量。尽管使用了催眠药,但血液透析患者的睡眠质量很差。尽管如此,在本研究中,荨麻和催眠药有助于维持睡眠质量的稳定性。血液透析患者的荨麻片可减少睡眠潜伏期并延长睡眠时间。

更新日期:2020-05-08
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