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Unusual presentation of brain abscess in a 23-month-old infant.
Child's Nervous System ( IF 1.4 ) Pub Date : 2020-05-07 , DOI: 10.1007/s00381-020-04623-5
Qingyong Xiang 1 , Chonggui Jiang 2 , Jiangzhi Wen 1 , Bin Deng 1
Affiliation  

BACKGROUD Pediatric brain abscesses usually occur as a consequence of predisposing conditions, such as ENT (ear, nose, and throat) infection and physical damage. But there are still a number of cryptogenic infection cases. METHODS We present an unusual cryptogenic infection case of multiple and multiloculated brain abscess in an infant, which was in the absence of ENT infection, meningitis, trauma, prior surgery, cyanotic heart disease, or immune defect. The child has no specific symptoms but keeping apathic and days of diarrhea. Deduced from clinical presentation and this case's DWI-MRI features, the onset of infection is hematogenous route, and the diarrhea could be the possible inducement. The child was successfully treated by surgical excision of big lesions and an 8-week total course of intravenous antibiotics. At the end of the 1-year follow-up period, the infant is well at both of physical and mental health. CONCLUSION The interest of this case is the silent clinical presentation and the possibly rare precipitating factor. To a certain extent, the variation trend of blood C-reactive protein level could predict the clinical effect of antibiotics in brain abscess case.

中文翻译:

23个月大婴儿脑脓肿的异常表现。

背景儿科脑脓肿通常是由诸如ENT(耳,鼻,喉)感染和身体损伤等易感疾病引起的。但是,仍然存在许多隐源性感染病例。方法我们在婴儿中发现了一个罕见的多发性多发性脑脓肿的隐源性感染病例,该病例没有ENT感染,脑膜炎,创伤,先前手术,发otic性心脏病或免疫缺陷。这个孩子没有特殊症状,但会保持冷漠和腹泻。从临床表现和本病例的DWI-MRI特征推导,感染的发生是血行途径,而腹泻可能是诱因。通过外科手术切除大的病灶并进行了为期8周的静脉抗生素疗程,成功治愈了该患儿。在1年的随访期末,婴儿的身体和心理健康状况都很好。结论该病例的兴趣在于沉默的临床表现和可能罕见的促发因素。血液中C反应蛋白水平的变化趋势在一定程度上可以预测脑脓肿病例中抗生素的临床疗效。
更新日期:2020-05-07
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