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Human health benefits of very-long-chain polyunsaturated fatty acids from microalgae.
Biochimie ( IF 3.9 ) Pub Date : 2020-05-07 , DOI: 10.1016/j.biochi.2020.04.022
Josselin Lupette 1 , Christoph Benning 2
Affiliation  

Microalgae are single-cell, photosynthetic organisms whose biodiversity places them at the forefront of biological producers of high-value molecules including lipids and pigments. Some of these organisms particular are capable of synthesizing n-3 very long chain polyunsaturated fatty acids (VLC-PUFAs), known to have beneficial effects on human health. Indeed, VLC-PUFAs are the precursors of many signaling molecules in humans involved in the complexities of inflammatory processes. This mini-review provides an inventory of knowledge on the synthesis of VLC-PUFAs in microalgae and on the diversity of signaling molecules (prostanoids, leukotrienes, SPMs, EFOX, isoprostanoids) that arise in humans from VLC-PUFAs.

中文翻译:

微藻类中超长链多不饱和脂肪酸对人体健康的益处。

微藻是单细胞的光合生物,其生物多样性将它们置于包括脂质和色素在内的高价值分子的生物生产者的最前沿。这些生物中的某些特别能够合成n-3个非常长的链多不饱和脂肪酸(VLC-PUFA),已知对人体健康具有有益作用。实际上,VLC-PUFA是人类许多信号分子的前体,参与炎症过程的复杂性。这份小型综述提供了有关微藻中VLC-PUFA的合成以及VLC-PUFAs在人体内产生的信号分子(前列腺素,白三烯,SPM,EFOX,异前列腺素)多样性的知识清单。
更新日期:2020-05-07
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