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Retrospective analysis of complications associated with retrobulbar bupivacaine in dogs undergoing enucleation surgery.
Veterinary Anaesthesia and Analgesia ( IF 1.7 ) Pub Date : 2020-05-06 , DOI: 10.1016/j.vaa.2020.04.007
Kyle J Bartholomew 1 , Lesley J Smith 1 , Ellison Bentley 1 , Michael R Lasarev 2
Affiliation  

Objective

To investigate complications associated with, and without, bupivacaine retrobulbar local anesthesia in dogs undergoing unilateral enucleation surgery.

Study design

Retrospective, observational study.

Animals

A total of 167 dogs underwent unilateral enucleation surgery via a transpalpebral approach.

Methods

Records from 167 dogs that underwent unilateral enucleation surgery that did (RB) or did not (NB) include retrobulbar bupivacaine anesthesia were reviewed, including anesthetic record, daily physical examination records, surgery report, patient discharge report and patient notes within 14 days of the surgery. Specific complications and severity were compared between RB and NB using the Wilcoxon rank-sum test. A ‘complication burden’ (0–5) comprising five prespecified complications was assigned and tested using rank-sum procedures. Statistical significance was set to 0.05.

Results

Group RB included 97 dogs and group NB 70 dogs. Dogs in NB had a 17.0 percentage points (points) greater risk for a postoperative recovery complication (38.6% versus 21.6%; 95% confidence interval: 3.0–30.6 points; p = 0.017). There was inconclusive evidence that dogs in group RB had a lower risk of requiring perioperative anticholinergic administration (12.4% versus 22.9%; 10.5 points; p = 0.073). Other complications were similar between groups RB and NB with risks that differed by <10 points. The risk of hemorrhage was similar between groups RB (22.7%) and NB (20.0%) with no significant difference in the level of severity (p = 0.664).

Conclusions and clinical relevance

In this retrospective study, the use of retrobulbar bupivacaine for enucleation surgery in dogs was not associated with an increased risk of major or minor complications.



中文翻译:

回顾性分析接受去核手术的犬后球布比卡因相关的并发症。

目的

调查与单侧去核手术的狗布比卡因后球局部麻醉有关和没有的并发症。

学习规划

回顾性观察研究。

动物

共有167只狗通过经睑入路进行了单侧摘除手术。

方法

对167只接受(RB)或不(NB)单侧摘除手术的狗的记录包括球后布比卡因麻醉,包括麻醉记录,每日体检记录,手术报告,出院报告和患者笔记记录。手术。使用Wilcoxon秩和检验比较RB和NB的特定并发症和严重程度。使用秩和程序分配并测试了包括五个预先指定的并发症的“并发症负担”(0-5)。统计显着性设为0.05。

结果

RB组包括97只狗和NB组70只狗。NB中的狗术后恢复并发症的风险高17.0个百分点(点)(38.6%21.6%; 95%置信区间:3.0-30.6点;p  = 0.017)。没有确凿的证据表明,RB组的犬需要围手术期抗胆碱能药物的风险较低(12.4%22.9%; 10.5分;p  = 0.073)。RB组和NB组之间的其他并发症相似,风险相差<10分。RB组(22.7%)和NB组(20.0%)的出血风险相似,严重程度无明显差异(p  = 0.664)。

结论与临床意义

在这项回顾性研究中,在犬的去核手术中使用后球布比卡因与增加主要或次要并发症的风险无关。

更新日期:2020-05-06
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