A spectroscopic ruler for G‐quadruplexes: Using 2D IR spectroscopy, we show that vibrational delocalization of guanine carbonyl modes is the primary origin of shifts in their infrared spectra upon G‐quadruplex assembly. Thus, the sizes of ordered G‐quadruplex motifs and structural transitions or defects that disrupt them can be detected spectroscopically.

中文翻译：

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红外光谱揭示了平行链DNA G四联体的首选基元大小和局部紊乱。

G-四链体的光谱尺：使用2D红外光谱，我们显示了鸟嘌呤羰基模态的振动离域化是G-四链体组装后其红外光谱移位的主要来源。因此，可以用光谱法检测有序的G-四链体基序的大小和破坏它们的结构转变或缺陷。