当前位置: X-MOL 学术Ann. N. Y. Acad. Sci. › 论文详情
Is the prevalence of anemia in children living at high altitudes real? An observational study in Peru.
Annals of the New York Academy of Sciences ( IF 4.295 ) Pub Date : 2020-05-06 , DOI: 10.1111/nyas.14356
Benita Maritza Choque-Quispe,Dulce E Alarcón-Yaquetto,Wilber Paredes-Ugarte,Arturo Zaira,Adelayda Ochoa,Gustavo F Gonzales

Anemia diagnosis in populations residing at high altitude (HA) involves an adjustment of hemoglobin (Hb) values owing to the increase in its concentration with altitude. The suitability of the adjustment has been questioned since Hb concentrations depend on how adapted a population is to HA. In Peru, anemia in preschool children (PSC) is a matter of severe public concern for its high rates; in the city of Puno (∼3800 MASL), for example, 67.7% of children under 3 years are diagnosed with anemia. Here, we conducted an observational study in PSC living at different altitudes in Puno to assess Hb, iron status, and the suitability of altitude-adjusted Hb values in defining iron deficiency anemia. After adjusting Hb, 65.66% of the population had anemia, while only 4.8% of PSC had anemia when using unadjusted Hb. Receiver-operating characteristic curves using total body iron (TBI) as a marker of iron status are presented. In the 36- to 59-month age group, unadjusted Hb performed better than altitude-adjusted Hb. In the 6- to 35-month age group, anemia (adjusted or unadjusted) was not associated with TBI. We conclude that Hb adjustment by altitude is not appropriate. Anemia at an early age is not entirely attributable to iron deficiency.
更新日期:2020-05-06

 

全部期刊列表>>
Springer化学材料学
骄傲月
如何通过Nature平台传播科研成果
跟Nature、Science文章学绘图
隐藏1h前已浏览文章
中洪博元
课题组网站
新版X-MOL期刊搜索和高级搜索功能介绍
ACS材料视界
x-mol收录
南开大学
朱守非
廖良生
郭东升
汪铭
伊利诺伊大学香槟分校
徐明华
中山大学化学工程与技术学院
试剂库存
天合科研
down
wechat
bug