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Assessment of the manifestations of atrial fibrillation in patients with acute cerebral stroke - a single-center study based on 998 patients.
Neurological Research ( IF 1.9 ) Pub Date : 2020-04-02 , DOI: 10.1080/01616412.2020.1746508
Paweł Warmus 1, 2 , Natalia Niedziela 1 , Maciej Huć 2 , Krzysztof Wierzbicki 1 , Monika Adamczyk-Sowa 1
Affiliation  

Aim of the Study: Cardioembolic stroke accounts for approximately 15-25% of ischemic strokes and is characterized by a poor prognosis. Atrial fibrillation (AF) is more commonly diagnosed in the elderly.The aim of the study was the assessment of the manifestations of AF in patients hospitalized due to cerebral stroke, with particular attention paid to newly diagnosed AF.Methods: A retrospective analysis was performed on 998 cerebral stroke patients. The data were analyzed for sex, age, cerebral stroke risk factors, drugs, NIHSS, RANKIN scores and ECG recordings on admission and at discharge.Results: The mean age of disease onset was 73 ± 16 years. Women accounted for 50.8% of patients. AF prior to hospital admission was diagnosed in 20.1% of patients, while de novo AF in 26.3% of patients during hospitalization. Hypercholesterolemia, hypertriglyceridemia and smoking were more commonly reported in ischemic stroke patients without AF compared to patients with ischemic stroke and AF. Ischemic heart disease, more frequent deaths, and a worse prognosis were more frequently observed in patients with ischemic stroke and AF compared to patients without AF. The first manifestation of AF in 25% of stroke patients was related to the period of the first 10 days of hospitalization.Discussion: The above data should prompt neurologists, cardiologists and family doctors to try to detect AF as a risk factor for ischemic stroke which worsens patient prognosis, prolongs hospital stay and contributes to increase in mortality, especially when more effective drug treatment is currently possible.

中文翻译:

评估急性脑卒中患者房颤的表现-基于998例患者的单中心研究。

研究目的:心脏栓塞性卒中约占缺血性卒中的15%至25%,并且预后不良。心房颤动(AF)在老年人中更常见。本研究的目的是评估因脑卒中住院的房颤的表现,尤其要注意新诊断的房颤。方法:进行回顾性分析998例脑卒中患者。对入院时和出院时的性别,年龄,脑卒中危险因素,药物,NIHSS,RANKIN得分和ECG记录进行分析。结果:平均发病年龄为73±16岁。女性占患者的50.8%。住院期间诊断出房颤的发生率为20.1%,而从头开始进行房颤的发生率为26.3%。高胆固醇血症,与患有缺血性中风和AF的患者相比,在没有AF的缺血性中风患者中,甘油三酸酯过多和吸烟更为普遍。与没有AF的患者相比,患有缺血性中风和AF的患者更经常观察到缺血性心脏病,更频繁的死亡和更差的预后。在25%的中风患者中,房颤的最初表现与住院的前10天有关。讨论:以上数据应促使神经科医生,心脏病医生和家庭医生尝试将房颤检测为缺血性中风的危险因素,恶化患者的预后,延长住院时间并增加死亡率,特别是在当前可能进行更有效的药物治疗时。
更新日期:2020-04-02
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