OBJECTIVE To compare sexual function and outcomes of quality of life of patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome after vaginal dilation and surgical procedures. STUDY DESIGN Cross-sectional study from January 2019 to June 2019. SETTING Tertiary teaching hospital. PATIENT(S) Women with MRKH syndrome treated with vaginal dilation (n = 88) or surgical procedures (n = 45). INTERVENTION WeChat-based questionnaires were distributed to every group member in our MRKH support group. MAIN OUTCOME MEASURE(S) Sexual functional were assessed by means of the Female Sexual Function Index (FSFI). Outcomes of quality of life were assessed by means of the 12-item World Health Organization Disability Assessment Schedule 2 (WHODAS2). Vaginal length was defined as the maximum depth of the placement of the vaginal mold. RESULT(S) The FSFI scores were similar between the dilation (24.49 ± 4.51) and surgery (23.79 ± 3.57) groups. Except for the higher orgasm score in the dilation group (9.96 ± 3.60 vs. 8.20 ± 2.67), the other dimensions of the FSFI were not significantly different between the groups. No significant differences were found in the WHODAS2 scores between the dilation group (median 8.33 [interquartile range 4.17-15.62]) and the surgery group (6.25 [2.08-14.58]). However, the vaginal length was significantly shorter in the dilation group (6.5 ± 2.04 cm) than in the surgery group (8.1 ± 1.59 cm). CONCLUSION(S) Although the vaginal length was shorter in the dilation therapy group than in the surgical therapy group, sexual function and quality of life were similar between these two groups. Vaginal dilation should be proposed as the first-line therapy for MRKH patients.

中文翻译：

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Mayer-Rokitansky-Küster-Hauser 综合征女性新阴道创建后的性功能和生活质量：阴道扩张术和外科手术的比较

目的 比较 Mayer-Rokitansky-Küster-Hauser (MRKH) 综合征患者在阴道扩张和手术后的性功能和生活质量结果。研究设计 2019 年 1 月至 2019 年 6 月的横断面研究。设置三级教学医院。患者 接受阴道扩张术（n = 88）或外科手术（n = 45）治疗的 MRKH 综合征女性。干预 基于微信的问卷已分发给我们 MRKH 支持小组的每个小组成员。主要结果测量通过女性性功能指数（FSFI）评估性功能。生活质量结果通过 12 项世界卫生组织残疾评估附表 2 (WHODAS2) 进行评估。阴道长度定义为阴道模具放置的最大深度。结果 (S) 扩张 (24.49 ± 4.51) 和手术 (23.79 ± 3.57) 组之间的 FSFI 评分相似。除了扩张组的性高潮得分较高（9.96 ± 3.60 vs. 8.20 ± 2.67）外，各组之间 FSFI 的其他维度没有显着差异。扩张组（中位数 8.33 [四分位距 4.17-15.62]）和手术组（6.25 [2.08-14.58]）之间的 WHODAS2 评分没有显着差异。然而，扩张组的阴道长度 (6.5 ± 2.04 cm) 明显短于手术组 (8.1 ± 1.59 cm)。结论(S) 尽管扩张治疗组的阴道长度比手术治疗组短，但两组的性功能和生活质量相似。