Staphylococcus aureus colonizes or causes infection in a multitude of niches within a mammalian host. Many of these niches are acidic, yet specific pH resistance mechanisms that facilitate survival have not been thoroughly investigated. This review discusses recent studies documenting known acid resistance mechanisms in S. aureus and other staphylococcal species. However, studies that clearly define the regulation of the acid resistance regulon and potential interactions with weak organic acids in specific niches of the host including the skin and gut are yet to be defined.

中文翻译：

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金黄色葡萄球菌的酸反应网络。

金黄色葡萄球菌在哺乳动物宿主内的许多壁colon中定植或引起感染。这些小生境中有许多是酸性的，但尚未深入研究促进生存的特定pH抵抗机制。这篇评论讨论了最近的研究，这些研究记录了金黄色葡萄球菌和其他葡萄球菌物种中已知的抗酸机制。然而，尚未明确定义耐酸调节剂的调节以及在包括皮肤和肠道在内的宿主特定壁ni中与弱有机酸的潜在相互作用的研究。