We aimed to compare the concentrations of serum cytokines in patients undergoing coronary angiography and finding their possible associations with metabolic syndrome. Twelve serum cytokines and growth factors (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, TNF-α, MCP-1, IFN-γ, EGF, and VEGF) were measured by sandwich chemiluminescence assays, on the Evidence Investigator^® system. There were significant differences regarding sex, height, weight, BMI, WC, HC, FPG, TG and HDL-C between those with and without MetS in patients undergoing angiography (p < .05). Serum concentrations of IL-6 and INF-γ were significantly higher in subjects with MetS, compared to those without MetS (p = .031 and p = .035, respectively). However, only serum IL-6 was associated with the presence of MetS (β = 1.215, CI = 1.047–1.409, p = .010). From several serum cytokines and growth factors assessed in patients, IL-6 was the only serum cytokine that was significantly different between those with and without MetS after correction for confounding factors.

我们的目的是比较接受冠状动脉造影的患者血清细胞因子的浓度，并发现它们与代谢综合征的可能关联。十二种血清细胞因子和生长因子（IL-1α，IL-1β，IL-2，IL-4，IL-6，IL-8，IL-10，TNF-α，MCP-1，IFN-γ，EGF和VEGF）通过夹心化学发光测定法，对证据研究者^®系统。在有和没有MetS的患者中，接受血管造影的患者在性别，身高，体重，BMI，WC，HC，FPG，TG和HDL-C方面存在显着差异（p  <.05）。与没有MetS的受试者相比，患有MetS的受试者的血清IL-6和INF-γ的浓度显着更高（p  = .031和p 分别为.035）。但是，只有血清IL-6与MetS的存在相关（β= 1.215，CI = 1.047-1.409，p  = .010）。从对患者进行的几种血清细胞因子和生长因子评估来看，校正混杂因子后，IL-6是唯一在有和没有MetS的患者之间明显不同的血清细胞因子。