Background: To compare the incidence and outcomes of ocular hypertension (OHT) after intravitreal injection of 0.7 mg dexamethasone (DEX) and 2 mg triamcinolone acetonide (IVT).Methods: In a single-center, retrospective comparative case series, all patients with at least 3 months follow-up receiving 2 mg IVT 3/1/2012 - 3/1/2017 or 0.7 mg dexamethasone 10/1/2014 - 3/1/2017 were included. Ocular hypertension was defined as an intraocular pressure (IOP) ≥ 25 mmHg. Patients with a minimum of 3 months follow-up were included. Patients receiving any other form of topical, oral, or intravitreal steroid were excluded.Results: 106 eyes in 100 patients receiving IVT and 114 eyes in 102 patients receiving DEX were included. The mean number of injections was 2.9 for patients receiving IVT and 2.4 for patients receiving DEX (p = .11). Fourteen eyes (13.2%) in 14 patients receiving IVT developed OHT compared to 17 eyes (15.1%) in 15 patients receiving DEX (p = .85). All cases of OHT were managed with IOP lowering drops or observation alone.Conclusions: Rates of ocular hypertension following 2 mg IVT and DEX are similar. All patients developing OHT were successfully managed without surgical intervention.

中文翻译：

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玻璃体内注射0.7mg地塞米松植入物对2mg曲安西龙后的眼压升高。

背景：比较玻璃体腔注射0.7 mg地塞米松（DEX）和2 mg曲安奈德（IVT）玻璃体腔注射后高眼压（OHT）的发生率和结果。方法：在单中心回顾性比较病例系列中，所有患者包括接受3 mg IVT 3/1/2012-3/1/2017或0.7 mg地塞米松10/1/2014-3/1/2017至少3个月的随访。高眼压定义为眼内压（IOP）≥25 mmHg。包括至少3个月的随访患者。结果：100例接受IVT的患者中106眼和102例接受DEX的患者中114眼被排除在外。接受IVT的患者平均注射次数为2.9，接受DEX的患者平均注射次数为2.4（p = .11）。十四只眼睛（13。在接受IVT的14例患者中，有2％会发展为OHT，而接受DEX的15例中有17眼（15.1％）（p = .85）。所有OHT病例均通过降低IOP或单独观察来治疗。结论：2 mg IVT和DEX后的高眼压发生率相似。所有发生OHT的患者均无需手术干预即可成功治疗。