BackgroundTo explore relationships among post-traumatic stress disorder (PTSD), depressive spectrum symptoms, and intrusiveness in subjects who survived the crash of a train derailed carrying liquefied petroleum gas and exploded causing a fire.MethodsA sample of 111 subjects was enrolled in Viareggio, Italy. AMOS version 21 (IBM Corp, 2012) was utilized for a structural equation model-path analysis to model the direct and indirect links between the exposure to the traumatic event, the occurrence of depressive symptoms, and intrusiveness. Subjects were administered with the SCID-IV (Structured Clinical Interview for DSM-IV), the Questionnaire for Mood Spectrum (MOODS-SR)-Last Month version, the Trauma and Loss Spectrum Questionnaire (TALS-SR), and the Impact of Event Scale-Revised version (IES-R).ResultsSixty-six (66/111; 59.4%) subjects met SCID-IV criteria for PTSD. Indices of goodness of fit were as followed: χ2/df = 0.2 P = .6; comparative fit index = 1 and root mean square error of approximation = 0.0001. A significant path coefficient for direct effect of potential traumatic events on depressive symptoms (β = 0.25; P < .04) and from depressive symptoms to intrusiveness (β = 0.34; P < .003) was found. An indirect effect was also observed: standardized value of potential traumatic events on intrusiveness was 0.86. The mediating factor of this indirect effect path was represented by depressive symptoms. Potential traumatic events explained 6.2% of the variance of depressive symptoms; 11.8% of the variance of intrusiveness was accounted for traumatic event and depressive symptoms.ConclusionsPath analysis led us to speculate that depression symptoms might have mediated the relationship between the exposure to potential traumatic events and intrusiveness for the onset of PTSD.

中文翻译：

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意大利火车碰撞幸存者的创伤后应激障碍：情绪谱失调和侵入性的作用

背景为了探讨在运输液化石油气的火车出轨并爆炸引起火灾中幸存下来的受试者的创伤后应激障碍 (PTSD)、抑郁谱系症状和侵入性之间的关系。方法在意大利维亚雷焦招募了 111 名受试者的样本. AMOS 版本 21 (IBM Corp, 2012) 用于结构方程模型路径分析，以模拟创伤事件暴露、抑郁症状发生和侵入性之间的直接和间接联系。受试者接受了 SCID-IV（DSM-IV 结构化临床访谈）、情绪谱问卷 (MOODS-SR)-上个月版本、创伤和损失谱问卷 (TALS-SR) 以及事件的影响规模修订版 (IES-R).ResultsSixty-6 (66/111; 59. 4%) 受试者符合 PTSD 的 SCID-IV 标准。拟合优度指标如下：χ2/df= 0.2磷= .6; 比较拟合指数 = 1，近似的均方根误差 = 0.0001。潜在创伤事件对抑郁症状的直接影响的显着路径系数（β= 0.25;磷< .04) 以及从抑郁症状到侵入性 (β= 0.34;磷< .003) 被发现。还观察到间接影响：潜在创伤事件对侵入性的标准化值为 0.86。这种间接影响路径的中介因素以抑郁症状为代表。潜在的创伤事件解释了 6.2% 的抑郁症状变异；11.8% 的侵入性方差被解释为创伤事件和抑郁症状。结论路径分析使我们推测，抑郁症状可能在潜在创伤事件的暴露与创伤后应激障碍发作的侵入性之间起中介作用。