Purpose

The Working Group of the Gynecological Tumor Committee of the Japanese Radiation Oncology Study Group (JROSG) published recommendations for contouring high-risk clinical target volumes (HR-CTV) on CT for 3-dimentional image-guided brachytherapy for cervical cancer. The purpose of this study was to compare HR-CTV delineated on CT, referencing recommendations from JROSG, with HR-CTV delineated on MRI, referencing consensus guidelines from the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC ESTRO).

Material and methods

Fourteen patients were evaluated. After the insertion of the CT/MR applicator into the patient, CT and MRI were performed. HR-CTV_MR was delineated on MRI for clinical examination and HR-CTV_CT was delineated on CT retrospectively referencing the MRI just before brachytherapy within a week. The volume and dosimetry of HR-CTV based on a 6 Gy dose of the Manchester system were evaluated.

Results

The median volumes of HR-CTV_MR and HR-CTV_CT were 24.4 ml (range, 13.6–50.4 ml) and 29.9 ml (range, 13.2–49.2 ml), respectively. Median D₉₀ of HR-CTV_MR and HR-CTV_CT were 6.7 Gy (range, 5.8–10.1 Gy) and 6.8 Gy (range, 5.1–10.4 Gy), respectively.

Conclusion

Somewhat difference could be seen between HR-CTV_MR and HR-CTV_CT.

中文翻译：

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参考日本放射肿瘤学研究小组 (JROSG) 的建议和欧洲居里治疗学会的共识声明指南，比较基于 CT 和基于 MRI 的宫颈癌影像引导近距离放射治疗的高风险临床目标体积治疗放射学和肿瘤学 (GEC ESTRO)。

目的

日本放射肿瘤学研究组 (JROSG) 妇科肿瘤委员会的工作组发布了在 CT 上勾画高风险临床靶区 (HR-CTV) 的建议，用于宫颈癌 3 维图像引导近距离放射治疗。本研究的目的是比较在 CT 上描绘的 HR-CTV，参考 JROSG 的建议，与在 MRI 上描绘的 HR-CTV，参考 Groupe Européen de Curiethérapie-欧洲治疗放射学和肿瘤学协会 (GEC ESTRO) 的共识指南。

材料与方法

评估了 14 名患者。在将 CT/MR 施加器插入患者体内后，进行了 CT 和 MRI。HR-CTV _MR在 MRI 上勾画用于临床检查，HR-CTV _CT在 CT 上勾画，在近距离放射治疗前一周内回顾性参考 MRI。评估了基于曼彻斯特系统 6 Gy 剂量的 HR-CTV 的体积和剂量学。

结果

HR-CTV _MR和 HR-CTV _CT的中位体积分别为 24.4 ml（范围，13.6-50.4 ml）和 29.9 ml（范围，13.2-49.2 ml）。HR-CTV _MR和 HR-CTV _{CT 的}中位 D ₉₀分别为 6.7 Gy（范围，5.8-10.1 Gy）和 6.8 Gy（范围，5.1-10.4 Gy）。

结论

HR-CTV _MR和 HR-CTV _CT之间可以看到一些差异。