We studied the effect of unstable ubiquitous endocrine disruptors (bisphenol A and triclosan) on the reproductive function of mature male Wistar rats. Animals of both experimental groups received bisphenol A and triclosan (homogeneity>97%) in a dose of 200 mg/kg daily for 2 months with food. The concentrations of disruptors were measured directly in the testicular tissue by gas chromatography with mass spectrometry (GC-MS). In both experimental groups, the concentrations of bisphenol A and triclosan in the testicular tissue significantly differed from the control (intact animals). Animals exposed to bisphenol A significantly differed by sperm parameters (total number, motility, and sperm morphology) from control rats. Animals receiving triclosan significantly differed from control rats only by the number of actively motile spermatozoa and the weight of the testicles.

中文翻译：

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暴露于双酚 A 和三氯生的白鼠精子的特征

我们研究了不稳定的普遍存在的内分泌干扰物（双酚 A 和三氯生）对成熟雄性 Wistar 大鼠生殖功能的影响。两个实验组的动物均以每天 200 mg/kg 的剂量接受双酚 A 和三氯生（均质性 > 97%），持续 2 个月随餐服用。通过气相色谱质谱联用 (GC-MS) 直接测量睾丸组织中干扰物的浓度。在两个实验组中，睾丸组织中双酚 A 和三氯生的浓度与对照（完整动物）显着不同。暴露于双酚 A 的动物与对照大鼠的精子参数（总数、运动性和精子形态）存在显着差异。