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Event-Related Potentials Elicited by Face and Face Pareidolia in Parkinson's Disease.
Parkinson's Disease ( IF 3.2 ) Pub Date : 2020-03-31 , DOI: 10.1155/2020/3107185
Gulsum Akdeniz 1 , Gonul Vural 2 , Sadiye Gumusyayla 2 , Hesna Bektas 2 , Orhan Deniz 2
Affiliation  

Background. Parkinson’s disease is associated with impaired ability to recognize emotional facial expressions. In addition to a visual processing disorder, a visual recognition disorder may be involved in these patients. Pareidolia is a type of complex visual illusion that permits the interpretation of a vague stimulus as something known to the observer. Parkinson’s patients experience pareidolic illusions. N170 and N250 waveforms are two event-related potentials (ERPs) involved in emotional facial expression recognition. Objective. In this study, we investigated how Parkinson’s patients process face and face-pareidolia stimuli at the neural level using N170, vertex positive potential (VPP), and N250 components of event-related potentials. Methods. To examine the response of face and face-pareidolia processing in Parkinson’s patients, we measured the N170, VPP, and N250 components of the event-related brain potentials in a group of 21 participants with Parkinson’s disease and 26 control participants. Results. We found that the latencies of N170 and VPP responses to both face and face-pareidolia stimuli were increased along with their amplitudes, and the amplitude of N250 responses decreased in Parkinson’s patients compared to the control group. In both control and Parkinson’s patients, face stimuli generated greater ERP amplitude and shorter latency in responses than did face-pareidolia stimuli. Conclusion. The results of our study showed that ERPs associated with face and also face-pareidolia stimuli processing are changed in early-stage neurophysiological activity in the temporoparietal cortex of Parkinson’s patients.

中文翻译:

帕金森病中面部和面部幻觉诱发的事件相关电位。

背景。帕金森病与识别情绪面部表情的能力受损有关。除了视觉处理障碍外,这些患者还可能涉及视觉识别障碍。Pareidolia 是一种复杂的视觉错觉,它允许将模糊的刺激解释为观察者已知的事物。帕金森病患者会出现幻觉。N170 和 N250 波形是涉及情绪面部表情识别的两个事件相关电位 (ERP)。客观的。在这项研究中,我们研究了帕金森病患者如何使用 N170、顶点正电位 (VPP) 和事件相关电位的 N250 分量在神经水平上处理面部和面部无视神经刺激。方法。为了检查帕金森病患者的面部和面部幻觉处理的反应,我们测量了一组 21 名帕金森病患者和 26 名对照参与者的事件相关脑电位的 N170、VPP 和 N250 成分。结果。我们发现,与对照组相比,帕金森病患者 N170 和 VPP 对面部和面部视错觉刺激反应的潜伏期随着幅度的增加而增加,而 N250 反应的幅度则降低。在对照组和帕金森氏症患者中,面部刺激产生的 ERP 振幅比面部无视刺激产生更大的反应时间和更短的反应潜伏期。结论。我们的研究结果表明,在帕金森病患者的颞顶叶皮层的早期神经生理活动中,与面部和面部视错觉刺激处理相关的 ERPs 发生了变化。
更新日期:2020-03-31
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