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Assessing the European impact of alcohol misuse and illicit drug dependence research: clinical practice guidelines and evidence-base policy.
BMJ Mental Health ( IF 5.2 ) Pub Date : 2020-05-01 , DOI: 10.1136/ebmental-2019-300124
Elena Pallari 1, 2 , Tayana Soukup 2 , Andri Kyriacou 3 , Grant Lewison 4
Affiliation  

Background Despite alcohol and illicit drug dependence being one of the most common diagnoses in Europe, there is heterogeneity of research evidence used in policy and practice. Objective We sought to (1) evaluate European research outputs on alcohol misuse and drug addiction in 2002–2018 in the Web of Science, (2) compare these with their burden of disease and (3) determine their impact in several ways. Methods A bibliometric research was undertaken including an assessment of the citation counts, the influence of research on members of national health advisory committees, and their contribution to the evidence base of clinical practice guidelines (CPGs). Findings There were 3201 analysed references cited in 28 CPGs across 11 European Countries on alcohol misuse and illicit drug abuse. Research conducted in the USA dominated both sets of CPGs, while many European countries were overcited relative to their research presence. The illicit drug research appeared to be adequate relative to the evidence of harm in Europe. However, alcohol misuse research appeared grossly inadequate to the harm it causes by a factor of 20. Conclusions The volume of research on illicit drug addiction is commensurate to the European burden, whereas alcohol misuse is far below what is needed to curb a significant source of harm. Clinical implications The research asymmetries call for attention to the causes of the problem. Development of research-based solutions to a serious social harm is needed, including minimum pricing and collaborative work to harmonise efforts on disease management and treatment practices across European countries.

中文翻译:

评估酒精滥用和非法药物依赖研究对欧洲的影响:临床实践指南和循证政策。

背景 尽管酒精和非法药物依赖是欧洲最常见的诊断之一,但政策和实践中使用的研究证据存在异质性。目标 我们试图 (1) 在 Web of Science 上评估 2002 年至 2018 年欧洲关于酒精滥用和药物成瘾的研究成果,(2) 将这些成果与其疾病负担进行比较,以及 (3) 以多种方式确定其影响。方法进行了文献计量研究,包括评估引用计数、研究对国家健康咨询委员会成员的影响以及他们对临床实践指南(CPG)证据基础的贡献。结果 11 个欧洲国家的 28 个 CPG 中引用了 3201 条经过分析的关于酒精滥用和非法药物滥用的参考文献。在美国进行的研究在两组 CPG 中都占主导地位,而许多欧洲国家的研究相对于其研究存在被过度引用。相对于欧洲的危害证据,非法药物研究似乎是充分的。然而,酒精滥用研究似乎严重不足,其造成的危害只有 20 倍。 结论 关于非法药物成瘾的研究量与欧洲的负担相称,而酒精滥用的研究远远低于遏制非法药物成瘾的一个重要来源所需的量。伤害。临床意义 研究的不对称性要求我们关注问题的原因。需要针对严重的社会危害制定基于研究的解决方案,包括最低定价和协作工作,以协调欧洲各国在疾病管理和治疗实践方面的努力。
更新日期:2020-05-01
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