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A new recombinant F1 antigen as a cost and time-effective tool for plague diagnosis.
Journal of Microbiological Methods ( IF 2.2 ) Pub Date : 2020-03-27 , DOI: 10.1016/j.mimet.2020.105903
Diego H C Tavares 1 , Matheus F Bezerra 2 , Franklin B Magalhães 3 , Thaíse Y V L Cavalcanti 2 , Camila C Xavier 2 , Nilma C Leal 2 , Alzira M P Almeida 2 , Christian R S Reis 2
Affiliation  

The Yersinia pestis capsular antigen F1 is widely used in plague laboratory diagnosis. Here, we describe the production of an F1 recombinant protein within reduced time and biosafety requirements. Its evaluation in hemagglutination tests indicated that the recombinant F1 can replace the conventional F1 protein for plague diagnosis.

中文翻译:

一种新的重组F1抗原可作为诊断鼠疫的经济高效的工具。

鼠疫耶尔森氏菌荚膜抗原F1被广泛用于瘟疫实验室诊断。在这里,我们描述了在减少的时间和生物安全性要求内生产F1重组蛋白的方法。在血凝试验中的评估表明,重组F1可以代替常规的F1蛋白用于鼠疫诊断。
更新日期:2020-03-27
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